ECFP with XGBoost

Why didn't I do this from first time...

So let's recall, this is from Random Forest

and this from SVM

and lastly from XGBoost

So, XGBoost gave the best accuracy, for a contest here.

But I guess it's all about how you use the model. SVM may get better with tuning as well. Hang on... How about parameter tuning of them... (But I do want to get into SOM too...)